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- bs-2679R-BF350
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100ul
| 产品编号 | bs-2679R-BF350 |
| 英文名称 | CD112 Rabbit pAb, BF350 conjugated |
| 中文名称 | BF350标记的细胞粘附分子CD112抗体 |
| 英文别名 | Nectin-2; Nectin2; Nectin 2; CD 112; CD112 antigen; Herpes virus entry mediator B; Herpes virus entry protein B; Herpesvirus entry mediator B; Herpesvirus entry protein B; Hve B; HveB; Poliovirus receptor like 2; Poliovirus receptor related 2(herpesvirus entry mediator B); Poliovirus receptor related 2; Poliovirus receptor related protein 2; Poliovirus receptor-related protein 2; Nectin cell adhesion molecule 2; HVEB; PRR 2; PRR2; PVRL 2; PVRL2; NECT2_HUMAN; PVRR 2; PVRR2. |
| 产品应用 | Flow-Cyt=1μg /test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD112 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Immunoglobulins > Receptors Microbiology > Interspecies Interaction > Host Virus Interaction |
| 亚基 | Can form trans-heterodimers with PVRL3/nectin-3. Interacts with CD226. Binds with low affinity to TIGIT. Interacts with herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudoRabies virus (PRV) envelope glycoprotein D; functions as an entry receptor for these viruses. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. |
| 组织特异性 | Ubiquitous. |
| 相似性 | Belongs to the nectin family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Probable cell adhesion protein. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudoRabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg /test} |
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文献和实验%。我的天敌很可怕，但是我也不是吃素的。Statista 2016年的一份统计报告预测了2020年全球十大抗癌药。看到没，这些都是我家族成员。 数据来源于www.statista.com 由于我家族成员众多，对付敌人的方式各不相同。我就给大家选择性的介绍一下吧。PD-1/PD-L1最近比较有名气，市场对它激烈程度无法想象，其市场峰值高达350亿美元。默沙东（Merck）、百时美施贵宝（BMS）、阿斯利康（AZN）、罗氏（Roche）均在火速推进各自的临床项目。唉呀妈呀
Characterization of Angiotensin II Receptors
. Opin. Nephrol. Hypertens. 3:112‐122. Timmermans, P.B.M.W.M., and Smith, R.D. 1994. Angiotensin II receptor subtypes: Selective antagonists and functional correlates. Eur
【共享】某机构发表的核酸相关研究的文章（EST,SNP等），PDF全文下载
A (2006) Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: Modes of action and impact on lethality J Pharmacol Exp Ther 318: 762-771 Elsharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M
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