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C21orf33 Rabbit pAb, PE conjug

ated(bs-15124R-PE)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-15124R-PE
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-15124R-PE
    英文名称C21orf33 Rabbit pAb, PE conjugated
    中文名称PE标记的21号染色体开放阅读框33抗体
    英文别名Chromosome 21 open reading frame 33; D21S2048E; ES 1; ES1; Es1 protein; ES1 protein homolog mitochondrial; GT335; HES 1; HES1; Human HES1 protein homolog to E.coli and zebrafish ES1 protein; Keio novel protein I; KNP I; KNPH; KNPI; Protein GT335; Protein KNP I; ES1_HUMAN; GATD3A
    产品应用Flow-Cyt=1μg/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human C21orf33
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria

    亚细胞定位Mitochondrion (Potential).
    组织特异性Ubiquitous, but strongly expressed in heartand skeletal muscle.
    相似性Belongs to the ES1 family._x000D_
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料KNP-I is a ubiquitously expressed mitochondrial protein that belongs to the ES1 family of proteins. It is a highly conserved protein with homologs identified in various species. This conserved nature suggests an important biological role for the KNP-I protein. The gene that encodes KNP-I (C21orf33) is located on human chromosome 21 in close proximity to a region (D21S25) associated with many genetic diseases. Down syndrome (DS), caused by an extra copy of chromosome 21, is the most common manifestation of trisomic chromosomes. It is likely that the overproduction of the C21orf33 gene product plays a role in the pathology of DS, while its chromosomal location suggests its likely involvement in D21S25 related diseases. While expressed in most tissue, highest expression of KNP-I is found in heart and muscle

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}
    {IF}{1:100-500}

     

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