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- bs-18760R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-18760R-Bio |
| 英文名称 | MECR Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的核受体结合因子MECR抗体 |
| 英文别名 | AI195831; CGI 63; FASN2B; Homolog of yeast 2 enoyl thioester reductase; HsNrbf-1; HsNrbf1; mecr; MECR_HUMAN; Mitochondrial 2 enoyl thioester reductase; mitochondrial; NRBF 1; NRBF-1; NRBF1; Nuclear receptor binding factor 1; Nuclear receptor-binding factor 1; OTTMUSP00000009996; RP23-13A13.1; Trans 2 enoyl CoA reductase, mitochondrial; Trans-2-enoyl-CoA reductase. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MECR |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Signal Transduction > Metabolism > Lipid metabolism Signal Transduction > Metabolism > Mitochondrial |
| 亚细胞定位 | Mitochondrion. |
| 组织特异性 | Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung. |
| 相似性 | Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. |
| 功能 | Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Mecr is a 373 amino acid mitochondrial protein that may play a role in fatty acid synthesis. Existing as two alternatively spliced isoforms, Mecr is highly expressed in cardiac and skeletal muscle, with lower levels found in pancreas, kidney, placenta and liver. Mecr forms a homodimer and belongs to the zinc-containing alcohol dehydrogenase family and quinone oxidoreductase subfamily. Mecr reduces trans-2-enoyl-CoA to acyl-CoA in an NADPH-dependent manner and is encoded by a gene that maps to human chromosome 1p35.3. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验相关实验
- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
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MECR Rabbit pAb, Biotin conjugated(bs-18760R-Bio)-100ul
￥2980
