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ATG4C Rabbit pAb, Biotin conju

gated(bs-4008R-Bio)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-4008R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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    产品编号bs-4008R-Bio
    英文名称ATG4C Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的自噬相关蛋白4C抗体
    英文别名APG4 autophagy 4 homolog C(S. cerevisiae); APG4 autophagy 4 homolog C; APG4 C; APG4-C; APG4C; ATG 4C; ATG4 autophagy related 4 homolog C(S. cerevisiae); Atg4c; ATG4C_HUMAN; AUT(S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase(S. cerevisiae); AUT like 1, cysteine endopeptidase; AUT like 3 cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; Autophagin 3; Autophagin-3; Autophagy related cysteine endopeptidase 3; Autophagy related protein 4 homolog C; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; Cysteine protease ATG4C; EC 3.4.22; FLJ14867; OTTHUMP00000010715.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ATG4C
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell Death > Autophagy > APG gene products

    Cancer > Cell Death > Autophagy > Signal Transduction

    Cancer > Oncoproteins/suppressors > Oncoproteins > Cell survival & death

    Cancer > Signal transduction > Autophagy

    Cardiovascular > Heart > Autophagy > APG gene products

    Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Other proteases

    Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy

    Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy > APG gene products

    亚细胞定位Cytoplasm (Probable).
    组织特异性Highly expressed in skeletal muscle, heart, liver and testis.
    相似性Belongs to the peptidase C54 family.
    功能Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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