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- Bioss
- bs-19195R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-19195R-AP |
| 英文名称 | NEK11 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的丝氨酸/苏氨酸蛋白激酶Nek11抗体 |
| 英文别名 | 4932416N14Rik; FLJ23495; NEK11; NEK11_HUMAN; NEK11S/L; Never in mitosis A-related kinase 11; NIMA(never in mitosis gene a) related kinase 11; NIMA(never in mitosis gene a)-related kinase 11; NIMA related kinase 11L; NIMA related kinase 11S; NIMA-related kinase 11; NimA-related protein kinase 11; Serine/threonine-protein kinase Nek11. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human NEK11 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Nucleus. Nucleus > nucleolus. Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells. |
| 组织特异性 | Poorly expressed in cerebellum, trachea, lung, appendix, and uterus. |
| 翻译后修饰 | Phosphorylated. |
| 相似性 | Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. _x000D_ Contains 1 protein kinase domain. |
| 功能 | Possible role in S-phase checkpoint mechanism. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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NEK11 Rabbit pAb, AP conjugated(bs-19195R-AP)-100ul
￥2980
