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- bs-11853R-BF594
- 2025年09月30日
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100ul
| 产品编号 | bs-11853R-BF594 |
| 英文名称 | HMX2 Rabbit pAb, BF594 conjugated |
| 中文名称 | BF594标记的同源盒蛋白H6亚型2抗体 |
| 英文别名 | H6 family homeo box 2; H6 family homeobox 2; H6 homeo box 2; H6L; HMX 2; HMX2; HMX2_HUMAN; Homeo box(H6 family) 2; Homeo box protein H6 family member 2; Homeobox(H6 family) 2; Homeobox protein H6 family member 2; Homeobox protein HMX2; Nkx5 2. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HMX2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the HMX homeobox family. _x000D_ Contains 1 homeobox DNA-binding domain. |
| 功能 | Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. HMX2 (H6 family homeobox 2), also known as H6L or Nkx5-2, is a 273 amino acid nuclear protein that belongs to the HMX homeobox family and contains one homeobox DNA-binding domain. HMX2 functions as a transcription factor that assists in specification of neuronal cell types and is essential for proper development of hypothalamus and inner ear. Hemizygous deletions of the gene encoding HMX2 are thought to lead to vestibular dysfunction, inner ear malformations and congenital sensorineural hearing loss. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
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A (2006) Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: Modes of action and impact on lethality J Pharmacol Exp Ther 318: 762-771 Elsharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M
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HMX2 Rabbit pAb, BF594 conjugated(bs-11853R-BF594)-100ul
￥2980
