Occludin Rabbit pAb, PE conjugated(bs-10011R-PE)-100ul

Occludin Rabbit pAb, PE conjug

ated(bs-10011R-PE)-100ul
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  • ¥2980
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  • bs-10011R-PE
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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    • 规格

      100ul

    产品编号bs-10011R-PE
    英文名称Occludin Rabbit pAb, PE conjugated
    中文名称PE标记的紧密连接蛋白抗体
    英文别名Occludin, Occludin-1; Occludin1; Occludin 1; FLJ08163; BLCPMG; FLJ18079; FLJ77961; FLJ94056; MGC34277; Occludin; OCLN; OCLN_HUMAN; Tight junction protein occludin.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Occludin
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Tight Junctions

    亚基Interacts with TJP1/ZO1 and with VAPA.
    亚细胞定位Membrane; Multi-pass membrane protein. Cell junction, tight junction.
    组织特异性Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis.
    翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR. Dephosphorylated by PTPRJ. May be phosphorylated by PKC during translocation to cell-cell contacts.
    相似性Belongs to the ELL/occludin family.
    Contains 1 MARVEL domain.
    功能May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. [provided by RefSeq].

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

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