HOOK3 Rabbit pAb, Biotin conj.(bs-17355R-Bio)-100ul产品图

HOOK3 Rabbit pAb, Biotin conj.

(bs-17355R-Bio)-100ul
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  • bs-17355R-Bio
  • 2026年10月14日
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      100ul

    产品编号bs-17355R-Bio
    英文名称HOOK3 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的HOOK3蛋白抗体
    英文别名FLJ31058; h-hook3; hHK3; HK3; HOOK3_HUMAN; OTTHUMP00000229200; Protein Hook homolog 3.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human HOOK3
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Trafficking > Golgi Proteins

    Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation

    亚细胞定位Cytoplasm > cytoskeleton. Golgi apparatus. Enriched at the cis-face of the Golgi complex (By similarity). Localizes to microtubule asters in prophase.
    相似性Belongs to the hook family.
    功能Probably serves as a target for the spiC protein from S‌‌almonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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