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- bsm-30030M-APC
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- 文献和实验
- 技术资料
- 规格：
25T/50T/100T
| 规格： | 25T | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 50T | 产品价格： | ￥1680.0 |
| 规格： | 100T | 产品价格： | ￥2680.0 |
| 产品编号 | bsm-30030M-APC |
| 英文名称 | human CD38 Mouse mAb, APC conjugated |
| 中文名称 | APC标记的小鼠抗人CD38单克隆抗体 |
| 英文别名 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD38_HUMAN; I-19; NIM-R5 antigen. |
| 产品应用 | Flow-Cyt=10ul/Test, IF=1:100-500, ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD38 |
| 亚型 | Mouse IgG1, k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 34 kDa |
| 实际分子量 | 45kDa |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Immunology > Adaptive Immunity > B Cells > CD Immunology > Adaptive Immunity > Regulatory T Cells Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Lymphoid > NK Cell Lineage Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage Stem Cells > Hematopoietic Progenitors > Surface Molecules |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 组织特异性 | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. |
| 相似性 | Belongs to the ADP-ribosyl cyclase family. |
| 功能 | Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |
| {IF} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
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文献和实验Method for Purification of Human Hematopoietic Stem Cells by Flow Cytometry
Negative/low marker CD38 Negative /low FITC, PE, APC
Reverse Transcriptase-PCR Analysis of Gene Expression in Hematopoietic Stem Cells
with anti c-kit MAb and the lineage-negative cells from human bone marrow are incubated with anti-CD34 and anti-CD38 MAb. With a starting population of 2–4 � 10e8 unfractionated mouse bone-marrow cells, a typical isolation procedure yields approx 2 � 10e4 FR
Human Th1/Th2 细胞群检测 CD3-PerCP-Cy5.5 PCP55-30004 CD4-FITC FITC-30005 IFN-γ-PE PE-30053 IL4-APC APC-30043 Mouse Th1/Th2 细胞群检测 CD3-PerCP-Cy5.5 PCP55-30002 CD4-FITC FITC-30128 IFN-γ-PE PE-30074 IL4-APC APC-30026 Human Treg细胞群检测 CD4-FITC FITC
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