PDXK | PNK Rabbit pAb, FITC conj.(bs-9035R-FITC)-100ul产品图

PDXK | PNK Rabbit pAb, FITC co

nj.(bs-9035R-FITC)-100ul
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  • bs-9035R-FITC
  • 2026年10月14日
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    • 详细信息
    • 技术资料
    • 规格:

      100ul

    产品编号bs-9035R-FITC
    英文名称PDXK Rabbit pAb, FITC conjugated
    中文名称FITC标记的吡哆醛激酶抗体
    英文别名PDXK.1; PDXK_HUMAN; PKH; PNK; Pyridoxal kinase; Pyridoxamine kinase; Pyridoxine kinase; Vitamin B6 kinase.
    产品应用Flow-Cyt=1ug/test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human PDXK
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    Metabolism > Pathways and Processes > Cofactors, Vitamins / minerals > Vitamins / minerals

    Signal Transduction > Metabolism > Vitamins / Minerals

    亚基Homodimer (Probable).
    亚细胞定位Cytoplasm.
    组织特异性Ubiquitous. Isoform 3 is detected in adult testis and spermatozoa.
    相似性Belongs to the pyridoxine kinase family.
    功能Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21.

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/test}

     

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