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- bs-12597R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-12597R-AP |
| 英文名称 | PDIA6 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的蛋白二硫异构酶A6抗体 |
| 英文别名 | Endoplasmic reticulum protein 5; ER protein 5; ERP5; P5; Protein disulfide isomerase A6; Protein disulfide isomerase associated 6; Protein disulfide isomerase family A member 6; Protein disulfide isomerase P5; Protein disulfide isomerase related protein; Thioredoxin domain containing 7(protein disulfide isomerase); Thioredoxin domain containing protein 7; TXNDC7. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PDIA6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Trafficking > ER Proteins |
| 亚基 | Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX. Interacts with MICA on the surface of tumor cells, leading to MICA disulfide bond reduction which is required for its release from tumor cells. Interacts with ITGB3 following platelet stimulation. |
| 亚细胞定位 | Endoplasmic reticulum. |
| 组织特异性 | Expressed in platelets (at protein level). |
| 相似性 | Belongs to the protein disulfide isomerase family. _x000D_ Contains 2 thioredoxin domains. |
| 功能 | May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protein disulfide isomerase (PDIA6) ia an enzyme belonging to the protein disulfide isomerase family. Structurally, it contains 2 thioredoxin domains and its function is to catalyze the rearrangement of -S-S- bonds in proteins. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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PDIA6 Rabbit pAb, AP conjugated(bs-12597R-AP)-100ul
￥2980
