Kir2.1 Rabbit pAb, BF680 conjugated(bs-17067R-BF680)-100ul

Kir2.1 Rabbit pAb, BF680 conju

gated(bs-17067R-BF680)-100ul
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  • ¥2980
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  • bs-17067R-BF680
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-17067R-BF680
    英文名称Kir2.1 Rabbit pAb, BF680 conjugated
    中文名称BF680标记的钾离子通道Kir2.1抗体
    英文别名Cardiac inward rectifier potassium channel; HHBIRK 1; HHBIRK1; HHIRK1; HIRK 1; hIRK1; Inward rectifier K; inwardly rectifying subfamily J member 2; IRK 1; IRK2_HUMAN; IRK1; KCNJ2; KIR2.1; LQT7; Potassium channel; Potassium channel inwardly rectifying subfamily J member 2; Potassium inwardly rectifying channel J2; Potassium inwardly rectifying channel subfamily J member 2; SQT 3; SQT3.
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Kir2.1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > Potassium Channels

    亚细胞定位Membrane.
    组织特异性Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain.
    相似性Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
    KCNJ2 subfamily.
    功能Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

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