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产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-3672R-Bio |
| 英文名称 | HSP22 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的热休克蛋白-22抗体 |
| 英文别名 | CMT2L; CRYAC; DHMN 2; DHMN2; E2 induced gene 1 protein; E2IG1; H11; Heat shock 22kDa protein 8; Heat shock protein 22; Heat shock protein beta 8; Hereditary motor neuropathy distal; HMN 2; HMN2; HSB8; HSPB 8; HSPB8; Protein kinase H11; Small stress protein like protein HSP22; Spinal muscular atrophy distal adult autosomal dominant; alpha crystallin C chain; Charcot Marie Tooth disease axonal type 2L; Charcot Marie Tooth disease spinal. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HSP22 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins |
| 亚基 | Monomer. Interacts with HSPB1. Interacts with DNAJB6. |
| 亚细胞定位 | Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock. |
| 组织特异性 | Predominantly expressed in skeletal muscle and heart. |
| 相似性 | Belongs to the small heat shock protein (HSP20) family. |
| 功能 | Displays temperature-dependent chaperone activity. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L). |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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HSP22 Rabbit pAb, Biotin conjugated(bs-3672R-Bio)-100ul
¥2980





