HSP22 Rabbit pAb, Biotin conjugated(bs-3672R-Bio)-100ul

HSP22 Rabbit pAb, Biotin conju

gated(bs-3672R-Bio)-100ul
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  • ¥2980
  • Bioss已认证
  • bs-3672R-Bio
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bs-3672R-Bio
    英文名称HSP22 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的热休克蛋白-22抗体
    英文别名CMT2L; CRYAC; DHMN 2; DHMN2; E2 induced gene 1 protein; E2IG1; H11; Heat shock 22kDa protein 8; Heat shock protein 22; Heat shock protein beta 8; Hereditary motor neuropathy distal; HMN 2; HMN2; HSB8; HSPB 8; HSPB8; Protein kinase H11; Small stress protein like protein HSP22; Spinal muscular atrophy distal adult autosomal dominant; alpha crystallin C chain; Charcot Marie Tooth disease axonal type 2L; Charcot Marie Tooth disease spinal.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human HSP22
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurology process > Neurodegenerative disease

    Signal Transduction > Protein Trafficking > Chaperones > Heat Shock Proteins

    亚基Monomer. Interacts with HSPB1. Interacts with DNAJB6.
    亚细胞定位 Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
    组织特异性Predominantly expressed in skeletal muscle and heart.
    相似性Belongs to the small heat shock protein (HSP20) family.
    功能Displays temperature-dependent chaperone activity.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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