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产品信息以Bioss网站为准
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100ul
| 产品编号 | bsm-33112M-PE |
| 英文名称 | CD41/ITGA2B Mouse mAb, PE conjugated |
| 中文名称 | PE标记的血小板膜糖蛋白Ⅱb(CD41)单克隆抗体 |
| 英文别名 | platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human ITGA2B |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Angiogenesis > Adhesion / ECM > Integrins Cardiovascular > Blood > Platelets Immunology > Cell Type Markers > CD > Platelets Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Murine Lineage Negative Stem Cells > Hematopoietic Progenitors > Myeloid > Thrombocytic Lineage |
| 亚细胞定位 | Membrane. |
| 相似性 | Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. |
| 功能 | Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |

Primary Antibody (green line): Mouse Anti-CD41 antibody (bsm-33112M-PE)
Dilution: 1ug/Test;
Isotype control(orange line):Normal Mouse IgG
Protocol
The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.
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文献和实验Fluorochrome Absorption and Emission Spectra
can be affected by the mAb conjugated. Thus while in the example above the PE-conjugate is brighter than the BD Cy-Chrome™ -conjugate, when analyzed on the BD FACSCalibur™ , for many mAbs the Cy-Chrome ™ -conjugate results in a brighter stain. Contact BD
Fluorochrome Absorption and Emission
can be affected by the mAb conjugated. Thus while in the example above the PE-conjugate is brighter than the BD Cy-Chrome™ -conjugate, when analyzed on the BD FACSCalibur™ , for many mAbs the Cy-Chrome ™ -conjugate results in a brighter stain. Contact BD
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