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CD41/ITGA2B Mouse mAb, PE conj

ugated(bsm-33112M-PE)-100ul
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  • ¥2980
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  • bsm-33112M-PE
  • 2025年10月15日
  • 产品信息以Bioss网站为准
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      100ul

    产品编号bsm-33112M-PE
    英文名称CD41/ITGA2B Mouse mAb, PE conjugated
    中文名称PE标记的血小板膜糖蛋白Ⅱb(CD41)单克隆抗体
    英文别名platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN.
    产品应用Flow-Cyt=1ug/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Mouse
    免疫原KLH conjugated synthetic peptide derived from human ITGA2B
    亚型IgG
    纯化方法affinity purified by Protein G
    克隆类型Monoclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Angiogenesis > Adhesion / ECM > Integrins

    Cardiovascular > Blood > Platelets

    Immunology > Cell Type Markers > CD > Platelets

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha

    Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Murine Lineage Negative

    Stem Cells > Hematopoietic Progenitors > Myeloid > Thrombocytic Lineage

    亚细胞定位Membrane.
    相似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    功能Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}

     

    产品细节图片1
    Blank control:HEL.
    Primary Antibody (green line): Mouse Anti-CD41 antibody (bsm-33112M-PE)
    Dilution: 1ug/Test;
    Isotype control(orange line):Normal Mouse IgG
    Protocol
    The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.

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    图标文献和实验
    相关实验
    • Fluorochrome Absorption and Emission Spectra

      can be affected by the mAb conjugated. Thus while in the example above the PE-conjugate is brighter than the BD Cy-Chrome™ -conjugate, when analyzed on the BD FACSCalibur™ , for many mAbs the Cy-Chrome ™ -conjugate results in a brighter stain. Contact BD

    • Fluorochrome Absorption and Emission

      can be affected by the mAb conjugated. Thus while in the example above the PE-conjugate is brighter than the BD Cy-Chrome™ -conjugate, when analyzed on the BD FACSCalibur™ , for many mAbs the Cy-Chrome ™ -conjugate results in a brighter stain. Contact BD

    • 三句话读懂一篇 CNS:饮酒引起 74 万新发癌症;干细胞研究为不孕不育患者带来福音……

      去甲基化酶2021 年 7 月 12 日,芝加哥大学何川团队联合上海科技大学刘如娟团队共同通讯在 Nature Cell Biology 杂志在线发表研究论文 ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing。揭示了ALKBH7 在细胞内主要对线粒体多顺反子 RNA 上的 m22G 和 m1A 进行去甲基化,进而调控线粒体 RNA 的加工成熟过程,证明 ALKBH7 是线粒体功能损失

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