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- Bioss
- bs-1500R-BF750
- 2025年09月30日
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100ul
| 产品编号 | bs-1500R-BF750 |
| 英文名称 | Cathepsin B Rabbit pAb, BF750 conjugated |
| 中文名称 | BF750标记的组织蛋白酶B抗体 |
| 英文别名 | Amyloid precursor protein secretase; APP secretase; APPS; Cathepsin B; CB; Cathepsin B1; CathepsinB; CPSB; CTSB; Cysteine protease; Preprocathepsin B; Cathepsin B heavy chain; Cathepsin B light chain; CATB_HUMAN. |
| 产品应用 | Flow-Cyt=1µg/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Cathepsin B heavy chain |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > ECM enzymes > Cathespins Cancer > Invasion/microenvironment > ECM > Cell adhesion Cancer > Invasion/microenvironment > ECM > Extracellular matrix Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Adhesion molecules ELISA kits Neuroscience > Cell Adhesion Proteins > Membrane Proteins Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > Other Enzymes |
| 亚基 | Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. Interacts with SRPX2. |
| 亚细胞定位 | Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| 相似性 | Belongs to the peptidase C1 family. |
| 功能 | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1µg/Test} |
| {IF} | {1:100-500} |
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Cathepsin B Rabbit pAb, BF750 conjugated(bs-1500R-BF750)-100ul
￥2980
