- ￥2980
- Bioss
- bs-11190R-AP
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
RANKL/CD254 Rabbit pAb, BF647 conjugated(bs-0747R-BF647)-100ul
￥2980
ZCCHC3/C20orf99 Rabbit pAb, BF594 conjugated(bs-19552R-BF594)-100ul
￥2980
GRK2 Rabbit pAb, BF647 conjugated(bs-1209R-BF647)-100ul
￥2980BTG1 Rabbit pAb, Cy5 conjugated(bs-7526R-Cy5)-100ul
￥2980
RIT1 Rabbit pAb, APC-Cy7 conjugated(bs-8392R-APC-Cy7)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-11190R-AP |
| 英文名称 | Complement component C9a Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的补体C9a抗体 |
| 英文别名 | C9 deficiency; C9a; C9 deficiency with dermatomyositis; CO9_HUMAN; Complement component 9; Complement component 9 deficiency; Complement component C9a; Complement component C9a; C9. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Complement component C9a |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Complement > MAC |
| 亚基 | Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9. |
| 亚细胞定位 | Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore. |
| 组织特异性 | Plasma. |
| 翻译后修饰 | Thrombin cleaves factor C9 to produce C9a and C9b. Phosphorylation sites are present in the extracellular medium. |
| 相似性 | Contains 1 EGF-like domain. Contains 1 LDL-receptor class A domain. Contains 1 MACPF domain. Contains 1 TSP type-1 domain. |
| 功能 | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Complement component C9a Rabbit pAb, AP conjugated(bs-11190R-AP)-100ul
￥2980
