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- bs-6023R-Cy5.5
- 2025年09月30日
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100ul
| 产品编号 | bs-6023R-Cy5.5 |
| 英文名称 | BST1 Rabbit pAb, Cy5.5 conjugated |
| 中文名称 | Cy5.5标记的骨髓基质干细胞抗原1抗体 |
| 英文别名 | Cyclic ADP ribose hydrolase 2; ADP ribosyl cyclase 2; Bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BST 1; BST1; BST-1; cADPr hydrolase 2; CD157; CD157 antigen; NAD(+) nucleosidase; BST1_HUMAN. |
| 产品应用 | Flow-Cyt=1μg/Test Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human BST1/CD157 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Adaptive Immunity > B Cells > CD Immunology > Immune System Diseases > Autoimmune Immunology > Innate Immunity > Myeloid Cells Signal Transduction > Signaling Pathway > Calcium Signaling |
| 亚基 | Homodimer. |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. |
| 组织特异性 | Widely expressed. |
| 相似性 | Belongs to the ADP-ribosyl cyclase family. |
| 功能 | Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Bone marrow stromal cell antigen 1 (BST1) is a pleiotropic ectoenzyme which belongs to the CD38 family and to the growing number of leukocyte surface molecules known to act independently as both receptors and enzymes. The BST1 molecule displays two distinct domains in its extracellular component. The first is implicated in the enzymic activities of the molecule (it synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores) and the second domain has adhesion/signalling properties.Bone marrow stromal cell antigen 1 facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg/Test} |
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BST1 Rabbit pAb, Cy5.5 conjugated(bs-6023R-Cy5.5)-100ul
￥2980
