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- bsm-30098M-BF405
- 2025年09月30日
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25T/50T/100T
| 规格： | 25T | 产品价格： | ￥680.0 |
|---|---|---|---|
| 规格： | 50T | 产品价格： | ￥1080.0 |
| 规格： | 100T | 产品价格： | ￥1680.0 |
| 产品编号 | bsm-30098M-BF405 |
| 英文名称 | human CD20 Mouse mAb, BF405 conjugated |
| 中文名称 | BF405标记的小鼠抗人CD20单克隆抗体 |
| 英文别名 | CD20_HUMAN; B-lymphocyte antigen CD20; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1; MS4A2; B1; CVID5; LEU-16; S7. |
| 产品应用 | Flow-Cyt=10ul/Test Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD20 |
| 亚型 | Mouse IgG2a |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 储存液 | 0.01M PBS (pH7.4), 0.5% BSA, 0.02% Proclin300. |
| 研究领域 | Cancer > Tumor immunology > Tumor-associated antigens Immunology > Adaptive Immunity > B Cells > CD Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed on B-cells. |
| 翻译后修饰 | Phosphorylated. Might be functionally regulated by protein kinase(s). |
| 相似性 | Belongs to the MS4A family. |
| 功能 | This protein may be involved in the regulation of B-cell activation and proliferation |
| 保存条件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {10ul/Test} |
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【翻译】Development trends for monoclonal antibody cancer therapeutics
7 and patients frequently developed antibodies to the mouse-derived proteins, which limited their utility8, 9. In addition, only certain murine mAb isotypes have been shown to effectively bind to and activate elements of the human immune
Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum
., Ivandic, B., Klingenspor, M., Klopstock, T., Kremmer, E., Mempel, M., Neschen, S., Ollert, M., Schulz, H., Suhre, K., Wolf, E., Wurst, W., Zimmer, A., and Hrabě de Angelis, M. 2011. Mouse phenotyping. Methods 53:120‐135
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