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- bs-5134R-Cy7
- 2025年09月30日
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100ul
| 产品编号 | bs-5134R-Cy7 |
| 英文名称 | BAG2 Rabbit pAb, Cy7 conjugated |
| 中文名称 | Cy7标记的Bcl-2结合抑凋亡蛋白2抗体 |
| 英文别名 | BAG 2; BAG-2; BAG family molecular chaperone regulator 2; BAG-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; dJ417I1.2; KIAA0576; MGC149462. |
| 产品应用 | Flow-Cyt=2ug/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human BAG2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Apoptosis Markers > Bcl 2 family Cancer > Cell Death > Apoptosis > Metabolism Cancer > Invasion/microenvironment > Apoptosis > Bcl 2 family Cell Biology > Apoptosis > Intracellular > Bcl2 Family Metabolism > Pathways and Processes > Metabolism processes > Apoptosis Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones |
| 相似性 | Contains 1 BAG domain. |
| 功能 | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/Test} |
| {IF} | {1:100-500} |
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文献和实验Fluorochrome Absorption and Emission Spectra
light at 488 nm for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes
Fluorochrome Absorption and Emission
for three-color flow cytometric analysis (Fig. 1). BD Biosciences Pharmingen also offers monoclonal antibodies and proteins conjugated to allophycocyanin (APC) and avidin conjugated to Texas Red™. Both of these dyes are useful in experiments
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