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SLC10A2 Rabbit pAb, Biotin con

jugated(bs-41358R-Bio)-100ul
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  • ￥2980
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  • bs-41358R-Bio
  • 2025年09月30日
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北京博奥森生物技术有限公司
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    产品编号bs-41358R-Bio
    英文名称SLC10A2 Rabbit pAb, Biotin conjugated
    中文名称Biotin标记的顶膜钠依赖性胆盐转运体蛋白抗体
    英文别名SLC10A2; Apical sodium dependent bile acid transporter; Apical sodium-dependent bile acid transporter; Ileal sodium dependent bile acid transporter; Ileal sodium-dependent bile acid transporter; Ileal sodium/bile acid cotransporter; ISBT; Na+bile acid cotransporter; Na+dependent ileal bile acid transporter; NTCP2; Sodium/taurocholate cotransporting polypeptide, ileal; solute carrier family 10(sodium/bile acid cotransporter family); Solute carrier family 10 member 2.
    产品应用WB=1:500-2000, IHC-P=1:100-500, ELISA=1:5000-10000, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原Recombinant mouse SLC10A2 protein
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Signal Transduction > Metabolism > Lipid metabolism

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚基Monomer and homodimer.
    亚细胞定位Membrane; Multi-pass membrane protein.
    相似性Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
    功能Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {ELISA}{1:5000-10000}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

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