SEPTIN14 | SEPT14 Rabbit pAb, AP conj.(bs-7772R-AP)-100ul产品图

SEPTIN14 | SEPT14 Rabbit pAb,

AP conj.(bs-7772R-AP)-100ul
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  • bs-7772R-AP
  • 2026年10月14日
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    北京博奥森生物技术有限公司
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      100ul

    产品编号bs-7772R-AP
    英文名称SEPT14 Rabbit pAb, AP conjugated
    中文名称AP标记的细胞分化蛋白SEPT14抗体
    英文别名SEPT14; SEPT 14; SEP14_HUMAN; Septin-14; Septin 14; Septin14; FLJ44060.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SEPT14
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell Division > Cytokinesis

    亚基Septins polymerize into heterooligomeric proteincomplexes that form filaments, and can associate with cellularmembranes, actin filaments and microtubules. GTPase activity isrequired for filament formation (By similarity). Interacts withSEPT9.
    亚细胞定位Cytoplasm.
    组织特异性Testis-specific.
    相似性Belongs to the septin family.
    功能SEPT14 is a filament-forming cytoskeletal GTPase. It may play a role in cytokinesis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Septin 14, also known as SEPT14, is a 432 amino acid protein that belongs to the septin family. The highly conserved septin family of GTP-binding cytoskeletal proteins is implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis and other cellular functions. Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. Septin 14 has a GTPase domain followed by a C-terminal coiled-coil domain characteristic of group II septins. Septin 14 interacted with all septins except those that are members of its phylogenetic cluster, including itself. Septin 14 shares highest identity (67%) with Septin 10. Expressed in testis and more weakly in fetal liver, tonsil and thymus, the Septin 14 protein is not detected in testicular cancer or other normal or cancer cell lines. The Septin 14 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 7p11.2.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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