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- bs-2872R-RBITC
- 2025年09月30日
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100ul
| 产品编号 | bs-2872R-RBITC |
| 英文名称 | SPHK2 Rabbit pAb, RBITC conjugated |
| 中文名称 | RBITC标记的鞘氨醇激酶2抗体 |
| 英文别名 | sphingosine kinase 2; SK 2; SPK 2; C76851; MGC102297; SPHK2_HUMAN. |
| 产品应用 | ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SPHK2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cell Biology > Apoptosis > Intracellular > Kinases Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Types of disease > Cancer Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR Signal Transduction > Signaling Pathway > Lipid Signaling > Lipid Kinases |
| 亚细胞定位 | Isoform 1: Cytoplasm. Membrane. Isoform 2: Lysosome membrane. |
| 相似性 | Contains 1 DAGKc domain. |
| 功能 | Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:100-500} |
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SPHK2 Rabbit pAb, RBITC conjugated(bs-2872R-RBITC)-100ul
￥2980
