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- bs-5120R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-5120R-HRP |
| 英文名称 | GTPBP3 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的26S蛋白酶调节亚型7抗体 |
| 英文别名 | 26S protease complex; MSS1; mammalian suppressor of sgv-1 of yeast; MSS1; Nbla10058; protease 26S subunit 7; proteasome 26S ATPase subunit 2; Proteasome 26S subunit ATPase 2; proteasome 26S subunit ATPase 2; Protein MSS1; PSMC2; putative protein product of Nbla10058; S7 antibody; PRS7_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MSS1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with NDC80 and SQSTM1. Interacts with PAAF1.Interacts with HIV-1 Tat. |
| 亚细胞定位 | Mitochondrial |
| 组织特异性 | Ubiquitously expressed. |
| 相似性 | Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. Contains 1 TrmE-type G (guanine nucleotide-binding)_x000D_ |
| 功能 | The GTPBP3 is the mitochondrial GTPase evolutionarily conserved from bacteria to mammals. GTPBP3 is ubiquitously expressed in various tissues. GTPBP3 localizes in mitochondrion. The human GTPBP3 is a deafness associated homolog of yeast MSS1. The allelic variants in GTPBP3 could modulate the phenotypic manifestation of human mitochondrial A1555G mutation. GTPBP3 may be involved in the 5 carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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GTPBP3 Rabbit pAb, HRP conjugated(bs-5120R-HRP)-100ul
￥2980
