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LHX2 Rabbit pAb, FITC conjugat

ed(bs-11200R-FITC)-100ul
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  • ¥2980
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  • bs-11200R-FITC
  • 2025年10月15日
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      100ul

    产品编号bs-11200R-FITC
    英文名称LHX2 Rabbit pAb, FITC conjugated
    中文名称FITC标记的调控胚胎干细胞分化蛋白Lhx2抗体
    英文别名hLhx2; Homeobox protein LH-2; Homeobox protein LH2; LH2; LHX2; LHX2_HUMAN; LIM homeobox 2; LIM homeobox protein 2; LIM HOX gene 2; LIM/homeobox protein Lhx2.
    产品应用Flow-Cyt=1μg/Test, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LHX2
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > HOX

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > LIM

    Neuroscience > Cell Type Marker > Neural Stem Cell marker

    Neuroscience > Neurology process > Neurogenesis

    Stem Cells > Hematopoietic Progenitors > Intracellular Molecules

    Stem Cells > Neural Stem Cells > Intracellular

    亚基Contains 1 homeobox DNA-binding domain. Contains 2 LIM zinc-binding domains.
    亚细胞定位Nucleus.
    相似性 Contains 1 homeobox DNA-binding domain.
    Contains 2 LIM zinc-binding omains.
    功能Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The overlapping expression of LHX1, LHX3, LHX4, Isl-1 and Isl-2 in developing motor neurons along the spinal column may influence the establishment of specific motor neuron subtypes. The human LHX2 gene maps to chromosome 9q33.3 and encodes a 389 amino acid protein. LHX2 is involved in early patterning of the telencephalon, where the neuroepithelium is first divided into cortical tissue and cortical hem.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}
    {IF}{1:100-500}

     

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    图标文献和实验
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