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- bs-41044R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-41044R-HRP |
| 英文名称 | CRF Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的促肾上腺皮质激素释放因子/促肾上皮质激素释放激素抗体 |
| 英文别名 | Corticoliberin; Corticoliberin precursor; Corticotropin releasing factor; Corticotropin releasing hormone; Corticotropin releasing hormone deficiency included; crf; crh; crh deficiency included; corticoliberin preproprotein; CRF_HUMAN; Corticotropin-releasing factor; CRH1; CRH; Corticotropin-releasing hormone. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CRF |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Endocrine system > Hypothalamic pituitary adrenal axis Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚基 | Interacts (via C-terminus) with CRFR1 (via N-terminalv extracellular domain). |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family. |
| 功能 | This hormone from hypothalamus regulates the release of corticotropin from pituitary gland. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Nov 2015] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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CRF Rabbit pAb, HRP conjugated(bs-41044R-HRP)-100ul
￥2980
