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- bs-11177R-HRP
- 2025年09月30日
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100ul
| 产品编号 | bs-11177R-HRP |
| 英文名称 | PI-15 Rabbit pAb, HRP conjugated |
| 中文名称 | HRP标记的肽酶抑制剂15抗体 |
| 英文别名 | Peptidase inhibitor 15; 25 kDa trypsin inhibitor; p25TI; Cysteine-rich secretory protein 8; CRISP-8; SugarCrisp; PI15_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PI-15 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Other protease inhibitors Neuroscience > Cell Adhesion Proteins > Proteases |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland. |
| 翻译后修饰 | N-glycosylated (Probable). |
| 相似性 | Belongs to the CRISP family. |
| 功能 | The soybean trypsin inhibitor was first crystallized by Kunitz in 1945 and is Serine protease inhibitor which displays weak inhibitory activity against trypsin. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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PI-15 Rabbit pAb, HRP conjugated(bs-11177R-HRP)-100ul
￥2980
