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- Bioss
- bs-8187R-AP
- 2025年09月30日
- 产品信息以Bioss网站为准
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100ul
| 产品编号 | bs-8187R-AP |
| 英文名称 | CSMD2 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的CSMD2蛋白抗体 |
| 英文别名 | CSMD2_HUMAN; CUB and Sushi(SCR repeat) domain; CUB and sushi domain-containing protein 2; CUB and sushi multiple domains protein 2; dJ1007G16.1; dJ1007G16.2; dJ947L8.1; KIAA1884. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CSMD2 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚细胞定位 | Cell membrane; Single-pass membrane protein (Potential). |
| 组织特异性 | Weakly expressed in most tissues, except in brain. Expressed at intermediate level in brain, including cerebellum, substantia nigra, hippocampus and fetal brain. Overexpressed in some head and neck cancer cell lines. |
| 相似性 | Belongs to the CSMD family._x000D_
Contains 14 CUB domains._x000D_ Contains 26 Sushi (CCP/SCR) domains. _x000D_ |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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CSMD2 Rabbit pAb, AP conjugated(bs-8187R-AP)-100ul
￥2980
