phospho-Caseine Kinase 1 alpha(Tyr294) Rabbit pAb, Cy7 conjugated(bs-12428R-Cy7)-100ul

phospho-Caseine Kinase 1 alpha

(Tyr294) Rabbit pAb, Cy7 conjugated(bs-12428R-Cy7)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-12428R-Cy7
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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      100ul

    产品编号bs-12428R-Cy7
    英文名称phospho-Caseine Kinase 1 alpha(Tyr294) Rabbit pAb, Cy7 conjugated
    中文名称Cy7标记的磷酸化酪蛋白激酶casein kinase Iα抗体
    英文别名Caseine Kinase 1 alpha(phospho Y294); p-CK1A(phospho Y294); Casein kinase 1 alpha 1; Casein kinase I isoform alpha; CK1; CK1A; CKI alpha; CKI-alpha; CKIa; Clock regulator kinase; Csnk1a1; Down regulated in lung cancer; HLCDGP1; KC1A_HUMAN; PRO2975.
    产品应用IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthesised phosphopeptide derived from human Caseine Kinase 1 alpha around the phosphorylation site of Tyr294
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases

    Stem Cells > Signaling Pathways > Wnt > Cytoplasmic

    亚基Monomer. Interacts with the Axin complex. Interacts with TUT1, leading to TUT1 phosphorylation.
    亚细胞定位Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis.
    相似性Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family.
    Casein kinase I subfamily.
    _x000D_ Contains 1 protein kinase domain.
    功能Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.

     

    应用推荐稀释比例
    {IF}{1:100-500}

     

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