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100ul
| 产品编号 | bs-12428R-Cy5.5 |
| 英文名称 | phospho-Caseine Kinase 1 alpha(Tyr294) Rabbit pAb, Cy5.5 conjugated |
| 中文名称 | Cy5.5标记的磷酸化酪蛋白激酶casein kinase Iα抗体 |
| 英文别名 | Caseine Kinase 1 alpha(phospho Y294); p-CK1A(phospho Y294); Casein kinase 1 alpha 1; Casein kinase I isoform alpha; CK1; CK1A; CKI alpha; CKI-alpha; CKIa; Clock regulator kinase; Csnk1a1; Down regulated in lung cancer; HLCDGP1; KC1A_HUMAN; PRO2975. |
| 产品应用 | IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthesised phosphopeptide derived from human Caseine Kinase 1 alpha around the phosphorylation site of Tyr294 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases Stem Cells > Signaling Pathways > Wnt > Cytoplasmic |
| 亚基 | Monomer. Interacts with the Axin complex. Interacts with TUT1, leading to TUT1 phosphorylation. |
| 亚细胞定位 | Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. |
| 相似性 | Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. _x000D_ Contains 1 protein kinase domain. |
| 功能 | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
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phospho-Caseine Kinase 1 alpha(Tyr294) Rabbit pAb, Cy5.5 conjugated(bs-12428R-Cy5.5)-100ul
¥2980





