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- bs-14127R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-14127R-AP |
| 英文名称 | CXXC4 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的CXXC型锌指蛋白4抗体 |
| 英文别名 | CXXC finger 4; CXXC finger protein 4; CXXC type zinc finger protein 4; CXXC-type zinc finger protein 4; Cxxc4; CXXC4_HUMAN; Dvl binding protein IDAX(inhibition of the Dvl and Axin complex); IDAX; Inhibition of the Dvl and axin complex protein; MGC149872. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CXXC4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cytoplasm. |
| 相似性 | Contains 1 CXXC-type zinc finger. |
| 功能 | Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Idax is a 198 amino acid cytoplasmic protein that functions as a negative regulator of the Wnt signaling pathway through its interaction with the PDZ domain of Dvl-1. Containing one CXXC-type zinc finger, Idax is expressed at high levels in brain, with lower levels in testis and thymus. The gene encoding Idax maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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CXXC4 Rabbit pAb, AP conjugated(bs-14127R-AP)-100ul
￥2980
