Human IL-6 Recombinant Rabbit mAb(bsm-10807R)-25ul/50ul/100ul

Human IL-6 Recombinant Rabbit

mAb(bsm-10807R)-25ul/50ul/100ul
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  • ¥800 - 2500
  • Bioss已认证
  • bsm-10807R
  • 2025年10月01日
  • 产品信息以Bioss网站为准
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    • 规格

      25ul/50ul/100ul

    规格:25ul产品价格:¥800.0
    规格:50ul产品价格:¥1400.0
    规格:100ul产品价格:¥2500.0
    产品编号bsm-10807R
    英文名称Human IL-6 Recombinant Rabbit mAb
    中文名称白介素6重组兔单抗
    英文别名Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma plasmacytoma growth factor; IFNB2; IL 6; IL6 protein; Interferon beta 2; Interleukin 6 (interferon beta 2); Interleukin 6; Interleukin-6; Interleukin6; IL6_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原Recombinant human IL-6 protein
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    理论分子量23 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors

    Cancer > Tumor immunology > Cytokines > Interleukins

    Immunology > Innate Immunity > Cytokines > Interleukins

    Metabolism > Types of disease > Metabolic disorders

    Metabolism > Types of disease > Obesity

    Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

    Neuroscience > Neurology process > Metabolism

    亚细胞定位Secreted.
    翻译后修饰N- and O-glycosylated.
    相似性Belongs to the IL-6 superfamily.
    功能Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    Human IL-6 Recombinant Rabbit
    HUVEC (H) cells were treated with or without LPS (0.5 μg/ml) for 24 hand Brefeldin A (300 ng/ml) for 20h, 25 μg total protein per lane of cell lysates (see on figure) probed with Human IL-6 monoclonal antibody, unconjugated (bsm-10807R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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