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Mono-Methyl-Histone H4 (K20) R

ecombinant Rabbit mAb(bsm-63227R)-25ul/50ul/100ul
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  • ¥800 - 2500
  • Bioss已认证
  • bsm-63227R
  • 2025年10月01日
  • 产品信息以Bioss网站为准
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      25ul/50ul/100ul

    规格:25ul产品价格:¥800.0
    规格:50ul产品价格:¥1400.0
    规格:100ul产品价格:¥2500.0
    产品编号bsm-63227R
    英文名称Mono-Methyl-Histone H4 (K20) Recombinant Rabbit mAb
    中文名称组蛋白H4(单甲基K20)重组兔单抗
    英文别名Histone H4; HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK.
    产品应用WB=1:1000-2000, IHC-P=1:100-200, IHC-F=1:100-200, ICC/IF=1:50-200, IF=1:50-200, IP=1:20-50, ChIP=1:20-50

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat
    抗体来源Rabbit
    免疫原A synthesized peptide derived from human Histone H4 around the methylation site of K20
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    理论分子量11 kDa
    实际分子量11kDa
    储存液10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
    研究领域

    Epigenetics and Nuclear Signaling > ChIP assays > ChIP antibodies

    Epigenetics and Nuclear Signaling > Histones > H4 > Acetylated

    亚基The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
    亚细胞定位Nucleus. Chromosome.
    翻译后修饰Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin._x000D_ Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
    相似性Belongs to the histone H4 family.
    功能Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    保存条件Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

     

    应用推荐稀释比例
    {WB}{1:1000-2000}
    {IHC-P}{1:100-200}
    {IHC-F}{1:100-200}
    {ICC/IF}{1:50-200}
    {IF}{1:50-200}
    {IP}{1:20-50}
    {ChIP}{1:20-50}

     

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