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- 详细信息
- 技术资料
- 应用范围:
产品信息以Bioss网站为准
- 规格:
25ul/50ul/100ul
| 规格: | 25ul | 产品价格: | ¥800.0 |
|---|---|---|---|
| 规格: | 50ul | 产品价格: | ¥1400.0 |
| 规格: | 100ul | 产品价格: | ¥2500.0 |
| 产品编号 | bsm-63201R |
| 英文名称 | IL-10 Recombinant Rabbit mAb |
| 中文名称 | 白细胞介素10重组兔单抗 |
| 英文别名 | IL10; CSIF; GVHDS; IL10A; TGIF; Interleukin-10. |
| 产品应用 | WB=1:500-2000, ICC/IF=1:50-200, Flow-Cyt=1:50-100 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human IL 10 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 21 kDa |
| 实际分子量 | 18kDa |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Cancer > Tumor immunology > Cytokines > Interleukins Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚基 | Homodimer. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. |
| 相似性 | Belongs to the IL-10 family. |
| 功能 | IL-10 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Interleukin-10 (IL-10) is an anti-inflammatory cytokine that is produced by T cells, NK cells, and macrophages. IL-10 initiates signal transduction by binding to a cell surface receptor complex consisting of IL-10 RI and IL-10 RII, leading to the activation of Jak1 and Tyk2 and phosphorylation of Stat3. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ICC/IF} | {1:50-200} |
| {Flow-Cyt} | {1:50-100} |
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IL-10 Recombinant Rabbit mAb(bsm-63201R)-25ul/50ul/100ul
¥800 - 2500





