- ￥1180 - 2800
- Bioss
- bsm-2200M
- 2025年10月01日
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bsm-2200M |
| 英文名称 | LDL Mouse mAb |
| 中文名称 | 低密度脂蛋白单克隆抗体 |
| 英文别名 | apolipoprotein; low density; low density lipoprotein; Low density lipoprotein. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Mouse |
| 免疫原 | Lipoprotein, low density from human plasma |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Lipid transport Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Lipoproteins Metabolism > Types of disease > Heart disease Metabolism > Types of disease > Metabolic disorders Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Secreted. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | LDL (low-density lipoprotein) is a type of lipoprotein that transports cholesterol and triglycerides from the liver to peripheral tissues. LDL enables fats and cholesterol to move within the water based solution of the blood stream. LDL also regulates cholesterol synthesis at these sites. The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
100 ng hLDL protein (bs-2200P) per lane probed with LDL monoclonal antibody respectively, unconjugated (bsm-2200M) at 1:1000 dilution and 4°C overnight incubation. Followed by corresponding conjugated secondary antibody incubation at r.t. for 60 min.
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LDL Mouse mAb(bsm-2200M)-50ul/100ul/200ul
￥1180 - 2800
