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- 规格：
50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-62982R |
| 英文名称 | SNAP25 Recombinant Rabbit mAb |
| 中文名称 | 突触相关蛋白25重组兔单抗 |
| 英文别名 | Synaptosomal-associated protein 25; SNAP-25; Super protein; SUP; Synaptosomal-associated 25 kDa protein; SNAP25; SNAP. |
| 产品应用 | WB=1:1000-2000, ICC/IF=1:50-200, IP=1:20-50 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human SNAP25 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 23 |
| 实际分子量 | 25 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Metabolism > Types of disease > Cancer Neuroscience > Cell Type Marker > Neuron marker > Synapse marker Neuroscience > Neurotransmission > Secretory Vesicles Neuroscience > Neurotransmission > Secretory Vesicles > SNAPs & SNAREs Signal Transduction > Protein Trafficking > Vesicle Transport > SNAPs & SNAREs |
| 亚基 | Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with CENPF, TRIM9, RIMS1, SNAPIN, OTOF and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1. |
| 亚细胞定位 | Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. |
| 组织特异性 | Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum. |
| 翻译后修饰 | Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association. |
| 相似性 | Belongs to the SNAP-25 family. Contains 2 t-SNARE coiled-coil homology domains. |
| 功能 | t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:1000-2000} |
| {ICC/IF} | {1:50-200} |
| {IP} | {1:20-50} |
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