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- Bioss
- bsm-62734R
- 2025年10月01日
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-62734R |
| 英文名称 | BCA2 Recombinant Rabbit mAb |
| 中文名称 | 乳腺癌相关基因2重组兔单抗 |
| 英文别名 | BCA2; RNF115. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human RNF115 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 34 |
| 实际分子量 | 37 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Cancer > Tumor biomarkers Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > RING Finger E3 Ligase Tags & Cell Markers > Cell Type Markers > Tumor Associated |
| 亚基 | Interacts with RAB7A._x000D_ |
| 亚细胞定位 | Cytoplasm, cytosol (By similarity). Note=The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes (By similarity). |
| 组织特异性 | Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells. |
| 翻译后修饰 | RING-type zinc finger-dependent and E2-dependent autoubiquitination._x000D_ |
| 相似性 | Contains 1 RING-type zinc finger._x000D_ |
| 功能 | Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | E3 ubiquitin-protein ligase that catalyzes the 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of various substrates and thereby plays a role in a number of signaling pathways including autophagy, innate immunity, cell proliferation and cell death. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Western blot analysis of PC-3 cell lysate. Using BCA2 (bsm-62734R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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BCA2 Recombinant Rabbit mAb(bsm-62734R)-50ul/100ul/25ul
￥800 - 2500
