- ￥800 - 2500
- Bioss
- bsm-62713R
- 2025年10月01日
- 产品信息以Bioss网站为准
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- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-62713R |
| 英文名称 | PTPRR Recombinant Rabbit mAb |
| 中文名称 | 蛋白酪氨酸磷酸酶受体PCPTP1重组兔单抗 |
| 英文别名 | ECPTP; NC PTPCOM1; PTPBR7; PTPRQ; PTPRR; PTPSL; Receptor type tyrosine protein phosphatase R. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human) |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human PTPRR |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 74 |
| 实际分子量 | 74 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Signal Transduction > Protein Phosphorylation > pTyr |
| 亚基 | Interacts with MAPKs |
| 亚细胞定位 | Cell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm. |
| 组织特异性 | Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus. |
| 相似性 | Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily. _x000D_ Contains 1 tyrosine-protein phosphatase domain. |
| 功能 | Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity). |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
25 ug total protein per lane of various lysates (see on figure) probed with PTPRR monoclonal antibody, unconjugated (bsm-62713R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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PTPRR Recombinant Rabbit mAb(bsm-62713R)-50ul/100ul/25ul
￥800 - 2500
