- ￥800 - 2500
- Bioss
- bsm-62642R
- 2025年10月01日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Cadherin Recombinant Rabbit mAb(bsm-63043R)-50ul/100ul/25ul
￥800
NET1 Rabbit pAb, APC-Cy7 conjugated(bs-6331R-APC-Cy7)-100ul
￥2980HRH4/GPCR105 Rabbit pAb, BF700 conjugated(bs-10165R-BF700)-100ul
￥2980
CYP2U1 Rabbit pAb, Biotin conjugated(bs-14153R-Bio)-100ul
￥2980
Tbx21 Rabbit pAb, Pacific Blue conjugated(bs-3599R-PacificBlue)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-62642R |
| 英文名称 | PLSCR3 Recombinant Rabbit mAb |
| 中文名称 | PLSCR3重组兔单抗 |
| 英文别名 | PLS3; Plscr3. |
| 产品应用 | WB=1:500-2000, Flow-Cyt=1:50-:100 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human PLSCR3 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 32 |
| 实际分子量 | 32 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Metabolism Cancer > Cell Death > Apoptosis > Mitochondrial Cardiovascular > Blood > Coagulation > Common Cell Biology > Apoptosis > Mitochondrial Metabolism > Pathways and Processes > Metabolism processes > Apoptosis Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Signal Transduction > Signaling Pathway > Lipid Signaling |
| 亚基 | Interacts with PDCD6 in a calcium-dependent manner. |
| 亚细胞定位 | Mitochondrion membrane; Single-pass type II membrane protein. |
| 组织特异性 | Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver. |
| 翻译后修饰 | Phosphorylation at Thr-21 by PKC/PRKCD upon apoptotic stimuli enhances flip-flop activity. |
| 相似性 | Belongs to the phospholipid scramblase family. |
| 功能 | May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of the phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer membrane of the mitochondria.Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {Flow-Cyt} | {1:50-:100} |
Western blot analysis of BxPC3 cell lysate. Using PLSCR3 (bsm-62642R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
The Hela (H) cells were fixed with 4% PFA (10 min at r.t.) and then permeabilized with 90% ice-cold methanol for 20 min at -20℃,the cells then were incubated in 5%BSA to block non-specific protein-protein interactions (30 min at r.t.), followed by secondary antibody incubation for 40 min at room temperature. Primary Antibody (green):Rabbit Anti-PLSCR3 antibody (bsm-62642R,1:100); Isotype Control (orange): Rabbit IgG (bs-0295P). Blank control (black): PBS. Acquisition of 20,000 events was performed.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
PLSCR3 Recombinant Rabbit mAb(bsm-62642R)-50ul/100ul/25ul
￥800 - 2500
