- ￥800 - 2500
- Bioss
- bsm-62467R
- 2025年10月01日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
PTPN1 Rabbit pAb, Biotin conjugated(bs-0182R-Bio)-100ul
￥2980
Integrin beta 1 Rabbit pAb, BF488 conjugated(bs-0486R-BF488)-100ul
￥2980RAC1+RAC2 Rabbit pAb, Biotin conjugated(bs-6154R-Bio)-100ul
￥2980
phospho-NMDAR2A (Tyr1325) Rabbit pAb, Pacific Blue conjugated(bs-3305R-PacificBlue)-100ul
￥2980
phospho-PRKCB (Thr642) Rabbit pAb, FITC conjugated(bs-5566R-FITC)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-62467R |
| 英文名称 | BRMS1 Recombinant Rabbit mAb |
| 中文名称 | 乳腺癌转移抑制基因1重组兔单抗 |
| 英文别名 | BRMS1 |
| 产品应用 | WB=1:1000-2000, IHC-P=1:100-200, IHC-F=1:100-200, ICC/IF=1:50-200, IF=1:50-200, IP=1:20-50 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human BRMS1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 28 |
| 实际分子量 | 28 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Tumor Suppressors |
| 亚基 | Belongs to the BRMS1 family. |
| 亚细胞定位 | Nucleus. Cytoplasm. Predominantly nuclear. |
| 组织特异性 | Expression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies. |
| 翻译后修饰 | Ubiquitinated by a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing SPOP, leading to proteasomal degradation. |
| 相似性 | Belongs to the BRMS1 family._x000D_ |
| 功能 | Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:1000-2000} |
| {IHC-P} | {1:100-200} |
| {IHC-F} | {1:100-200} |
| {ICC/IF} | {1:50-200} |
| {IF} | {1:50-200} |
| {IP} | {1:20-50} |
Western blot analysis of HeLa cell lysate. Using BRMS1 (bsm-62467R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
4% Paraformaldehyde-fixed Hela (H) cell; Triton X-100 at r.t. for 20 min; Antibody incubation with (BRMS1) monoclonal Antibody, unconjugated (bsm-62467R) 1:100, 90 min at 37°C; followed by conjugated Goat Anti-Rabbit IgG antibody (green, bs-40295G-FITC) at 37°C for 90 min, DAPI (blue, C02-04002) was used to stain the cell nuclei. PBS instead of the primary antibody was used as the blank control.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
BRMS1 Recombinant Rabbit mAb(bsm-62467R)-50ul/100ul/25ul
￥800 - 2500
