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VEGF-D Recombinant Rabbit mAb(

bsm-62367R)-50ul/100ul/25ul
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  • ￥800 - 2500
  • Bioss已认证
  • bsm-62367R
  • 2025年10月01日
  • 产品信息以Bioss网站为准
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    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      50ul/100ul/25ul

    规格：50ul产品价格：￥1400.0
    规格：100ul产品价格：￥2500.0
    规格：25ul产品价格：￥800.0
    产品编号 bsm-62367R
    英文名称 VEGF-D Recombinant Rabbit mAb
    中文名称 血管内皮生长因子D型重组兔单抗
    英文别名 FIGF; VEGFD.
    产品应用 WB=1:500-2000, IHC-P=1:100-200, IHC-F=1:100-200, ICC/IF=1:50-200, IF=1:50-200, Flow-Cyt=1:50-100

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.
    交叉反应 Human, Mouse, Rat
    抗体来源 Rabbit
    免疫原 A synthesized peptide derived from human VEGF D
    亚型 IgG
    性状 Liquid
    纯化方法 affinity purified by Protein A
    克隆类型 Recombinant
    理论分子量 40
    实际分子量 40
    储存液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
    研究领域

    Cancer > Growth factors > VEGF

    Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors

    Cardiovascular > Angiogenesis > Growth Factors > VEGF > VEGF

    Signal Transduction > Growth Factors/Hormones > VEGF
    亚基 Homodimer; non-covalent and antiparallel.
    亚细胞定位 Secreted.
    组织特异性 Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
    翻译后修饰 Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
    相似性 Belongs to the PDGF/VEGF growth factor family.
    功能 Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors. [SUBUNIT] Homodimer; non-covalent and antiparallel.
    保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
    注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料 Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

     

    应用 推荐稀释比例
    {WB} {1:500-2000}
    {IHC-P} {1:100-200}
    {IHC-F} {1:100-200}
    {ICC/IF} {1:50-200}
    {IF} {1:50-200}
    {Flow-Cyt} {1:50-100}

     

    Western blot analysis of Caco-2 cell lysate. Using VEGF-D (bsm-62367R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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