Munc18-1 Recombinant Rabbit mAb(bsm-62220R)-50ul/100ul/25ul

Munc18-1 Recombinant Rabbit mA

b(bsm-62220R)-50ul/100ul/25ul
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  • ¥800 - 2500
  • Bioss已认证
  • bsm-62220R
  • 2025年10月01日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/25ul

    规格:50ul产品价格:¥1400.0
    规格:100ul产品价格:¥2500.0
    规格:25ul产品价格:¥800.0
    产品编号bsm-62220R
    英文名称Munc18-1 Recombinant Rabbit mAb
    中文名称神经突触前膜胞内蛋白18重组兔单抗
    英文别名P67; NSEC1; UNC18; RBSEC1; MUNC18-1.
    产品应用WB=1:500-2000, IHC-P=1:100-200, IHC-F=1:100-200, ICC/IF=1:50-200, IF=1:50-200

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat)
    抗体来源Rabbit
    免疫原A synthesized peptide derived from human Syntaxin binding protein 1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    理论分子量68
    实际分子量65
    储存液10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy

    Metabolism > Types of disease > Cancer

    Neuroscience > Cell Type Marker > Neuron marker > Synapse marker

    Neuroscience > Neurotransmission > Secretory Vesicles > Munc18

    亚基Binds SYTL4. Interacts with STX1A.
    亚细胞定位Cytoplasm. Membrane; Peripheral membrane protein.
    组织特异性Brain and spinal cord. Highly enriched in axons.
    相似性Belongs to the STXBP/unc-18/SEC1 family.
    功能May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
    保存条件Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-200}
    {IHC-F}{1:100-200}
    {ICC/IF}{1:50-200}
    {IF}{1:50-200}

     

    Munc18-1 Recombinant Rabbit mA
    25 ug total protein per lane of various lysates (see on figure) probed with Munc18-1 monoclonal antibody, unconjugated (bsm-62220R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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