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50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-61484R |
| 英文名称 | GDNF Recombinant Rabbit mAb |
| 中文名称 | 胶质细胞源性神经营养因子重组兔单抗 |
| 英文别名 | ATF1; ATF2; gdnf; HFB1 GDNF; hGDNF; HSCR3. |
| 产品应用 | WB=1:500-2000, Flow-Cyt=1:50-100 Not yet tested in other applications. |
| 交叉反应 | Human, Rat (Mouse) |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human GDNF |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 24 |
| 实际分子量 | 24 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Developmental Biology > Organogenesis > Excretory system development > Kidney development Neuroscience > Neurology process > Growth and Development > Neurotrophins Neuroscience > Neurology process > Neurodegenerative disease > Amyotrophic lateral sclerosis Neuroscience > Neurology process > Neurodegenerative disease > Parkinson's disease |
| 亚基 | Homodimer; disulfide-linked. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change. |
| 相似性 | Belongs to the TGF-beta family. GDNF subfamily. |
| 功能 | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {Flow-Cyt} | {1:50-100} |
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