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- bsm-61421R
- 2025年09月30日
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- 规格：
50ul/100ul/25ul
| 规格： | 50ul | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2500.0 |
| 规格： | 25ul | 产品价格： | ￥800.0 |
| 产品编号 | bsm-61421R |
| 英文名称 | MINA53 Recombinant Rabbit mAb |
| 中文名称 | 组蛋白赖氨酸去甲基化酶MINA重组兔单抗 |
| 英文别名 | Histone lysine demethylase MINA; MDIG; MINA; NO52; ROX. |
| 产品应用 | WB=1:1000-2000, ICC/IF=1:50-200 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | A synthesized peptide derived from human Ribosomal oxygenase 2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Recombinant |
| 理论分子量 | 53 |
| 实际分子量 | 53 |
| 储存液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Jumonji containing proteins |
| 亚细胞定位 | Nucleus. Nucleus; nucleolus. |
| 组织特异性 | Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines. |
| 相似性 | Belongs to the MINA53/NO66 family. _x000D_ Contains 1 JmjC domain. |
| 功能 | Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| 保存条件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:1000-2000} |
| {ICC/IF} | {1:50-200} |
Western blot analysis of A431 cell lysate. Using MINA53 (bsm-61421R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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MINA53 Recombinant Rabbit mAb(bsm-61421R)-50ul/100ul/25ul
￥800 - 2500
