- ￥2980
- Bioss
- bs-13398R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-13398R-AP |
| 英文名称 | GSTA1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的谷胱甘肽S转移酶α1抗体 |
| 英文别名 | Glutathione S alkyltransferase A1; Glutathione S aralkyltransferase A1; Glutathione S aryltransferase A1; Glutathione S transferase 2; Glutathione S transferase A1; Glutathione S transferase alpha 1; Glutathione S transferase Ha subunit 1; Glutathione S-transferase A1; GST 2; GST class alpha; GST class alpha 1; GST class alpha member 1; GST class-alpha member 1; GST epsilon; GST HA subunit 1; GST, class alpha, 1; GST-epsilon; GST2; GSTA 1; GSTA1 1; GSTA1 protein; GSTA1-1; GSTA1_HUMAN; GTH 1; GTH1; HA subunit 1; MGC131939; OTTHUMP00000016611; S(hydroxyalkyl)glutathione lyase A1. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GSTA1/Glutathione S Transferase alpha |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress Signal Transduction > Metabolism > Energy Metabolism Tags & Cell Markers > Fusion / Marker Proteins > GST |
| 亚基 | Homodimer or heterodimer of GSTA1 and GSTA2. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Liver. |
| 翻译后修饰 | S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561. |
| 相似性 | Belongs to the GST superfamily. Alpha family. _x000D_ Contains 1 GST C-terminal domain. _x000D_ Contains 1 GST N-terminal domain. |
| 功能 | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. GSTs are differentially expressed in lung, liver and kidney tissue. Three isoforms, GSTA1-1, GSTA1-4 and GSTM1, localize to the mitochondria in addition to the cytoplasm. In normal and transformed cells, the oncoprotein Myb transcriptionally upregulates GSTM1. This isoform shows high specific activity for aflatoxin B1 epoxide conjugation, suggesting an important role for this interaction in the defense against both chemical and oxidative stress. The C-terminal domain of GSTA1 may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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GSTA1 Rabbit pAb, AP conjugated(bs-13398R-AP)-100ul
￥2980
