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- bs-14599R-Bio
- 2026年10月14日
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- 技术资料
- 规格：
100ul
| 产品编号 | bs-14599R-Bio |
| 英文名称 | ENPP4 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的ENPP4蛋白抗体 |
| 英文别名 | 4933413N07Rik; AA986363; AI195364; E-NPP 4; Ectonucleotide pyrophosphatase/phosphodiesterase 4(putative); Ectonucleotide pyrophosphatase/phosphodiesterase family member 4; ENPP4; ENPP4_HUMAN; Gm90; KIAA0879; mKIAA0879; NPP-4; NPP4. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ENPP4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed on the surface of vascular endothelia. |
| 相似性 | Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. |
| 功能 | Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ENPP4 is a 453 amino acid single-pass type I membrane protein that belongs to the nucleotide pyrophosphatase/phosphodiesterase family. The gene that encodes NPP4 consists of approximately 16,736 bases and maps to human chromosome 6p21.1. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene, and Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins are also located on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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ENPP4 | NPP-4 Rabbit pAb, Biotin conj.(bs-14599R-Bio)-100ul
￥2980
