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- bs-14591R-Bio
- 2025年09月30日
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100ul
| 产品编号 | bs-14591R-Bio |
| 英文名称 | ENDOD1 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的核酸内切酶结构域蛋白1抗体 |
| 英文别名 | C85344; ENDD1_HUMAN; Endonuclease domain containing 1; Endonuclease domain-containing 1 protein; KIAA0830. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, ELISA=1:5000-10000, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ENDOD1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the DNA/RNA non-specific endonuclease family. |
| 功能 | May act as a DNase and a RNase. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ENDOD1 is a 500 amino acid secreted protein that belongs to the DNA/RNA non-specific endonuclease family. ENDOD1 is thought to act as a DNase and an RNase. The gene that encodes ENDOD1 maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
| {IF} | {1:100-500} |
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ENDOD1 Rabbit pAb, Biotin conjugated(bs-14591R-Bio)-100ul
￥2980
