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- 技术资料
- 应用范围:
产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-10778R-Bio |
| 英文名称 | FBXL20 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的FBXL20蛋白抗体 |
| 英文别名 | F box/LRR repeat protein 20; F box/LRR repeat protein 2 like; F box/LRR repeat protein 20; Fbl2; Fbl20; F box and leucine rich repeat protein 20; MGC15482; SCR; SCRAPPER; FXL20_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FBXL20 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > F Box E3 Ligase Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > SCF Complex E3 Ligase Neuroscience > Neurotransmission > Intracellular Signaling > Regulation Neuroscience > Neurotransmitter > Transporters > Glutamate |
| 亚基 | Interacts with SKP1 and CUL1. |
| 亚细胞定位 | Cytoplasmic. |
| 相似性 | Contains 1 F-box domain._x000D_
Contains 13 LRR (leucine-rich) repeats. |
| 功能 | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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FBXL20 Rabbit pAb, Biotin conjugated(bs-10778R-Bio)-100ul
¥2980





