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产品信息以Bioss网站为准
- 规格:
100ul
| 产品编号 | bs-1190R-AP |
| 英文名称 | ECE1 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的内皮素转化酶1抗体 |
| 英文别名 | ECE 1; ECE-1; Endothelin converting enzyme 1; ECE1_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ECE1 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Cardiovascular > Vasculature > Endothelium Cardiovascular > Vasculature > Vasoconstriction Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Signal Transduction > Growth Factors/Hormones > Hormones |
| 亚基 | Homodimer; disulfide-linked. |
| 亚细胞定位 | Cell Membrane. Single pass type II membrane protein. |
| 组织特异性 | All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney. |
| 相似性 | Belongs to the peptidase M13 family. |
| 功能 | Converts big endothelin-1 to endothelin-1. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Sep 2009]. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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ECE1 Rabbit pAb, AP conjugated(bs-1190R-AP)-100ul
¥2980





