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100ul
| 产品编号 | bs-12042R-Bio |
| 英文名称 | T2R60 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的味觉受体蛋白家族2亚基60抗体 |
| 英文别名 | T2R56; TAS2R60; Taste receptor type 2 member 60; T2R60_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human T2R60 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cell Membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
| 相似性 | Belongs to the G-protein coupled receptor T2R family. |
| 功能 | T2R60 may play a role in the perception of bitterness and is gustducin-linked. It is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验相关实验
- or triple-labeling immunofluorescence, it is necessary to use primary antibodies raised in different host species such as mouse, rabbit, and goat. However, in many cases, suitable primary antibodies raised in different species are unavailable
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T2R60 Rabbit pAb, Biotin conjugated(bs-12042R-Bio)-100ul
¥2980








