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- bs-12038R-Cy3
- 2025年09月30日
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100ul
| 产品编号 | bs-12038R-Cy3 |
| 英文名称 | CLIC6 Rabbit pAb, Cy3 conjugated |
| 中文名称 | Cy3标记的氯离子通道蛋白6抗体 |
| 英文别名 | Chloride channel form A; Chloride intracellular channel 6; Chloride intracellular channel protein 6; CLIC1L; Clic6; CLIC6_HUMAN; Parchorin. |
| 产品应用 | Flow-Cyt=2ug/Test, IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CLIC6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Dopamine Receptors Signal Transduction > Metabolism > Plasma Membrane > Channels |
| 亚基 | Interacts with dopamine receptors DRD2, DRD3 and DRD4 |
| 亚细胞定位 | Cytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane. |
| 组织特异性 | Expressed in brain, placenta, pancreas and liver. |
| 翻译后修饰 | Phosphorylated. |
| 相似性 | Belongs to the chloride channel CLIC family. _x000D_ Contains 1 GST C-terminal domain. |
| 功能 | May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | CLIC6 (chloride intracellular channel 6) is believed to play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. The CLIC6 gene is a rare example of large-scale segmental paralogy in which a large (approximately 500 kb) segment on human chromosome (HC) 21 (21q22) is triplicated on HC 1 and HC 6. CLIC6 is also known to interact with dopamine receptors DRD2, DRD3 and DRD4. CLIC6 is primarily expressed in the cytoplasm, however, upon chloride ion efflux from the cell, CLIC6 is translocated to the plasma membrane. CLIC6 has been identified in brain, placenta, pancreas and liver. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/Test} |
| {IF} | {1:100-500} |
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文献和实验相关实验
Construction and Use of Glycan Microarrays
) Printing buffer (see recipe ) Controls: unmodified BSA and HSA (negative controls) and BSA conjugated with Cy3 or Alexa Fluor 647
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CLIC6 Rabbit pAb, Cy3 conjugated(bs-12038R-Cy3)-100ul
￥2980
